MALIGNANT GASTROINTESTINAL STROMAL TUMOR OF THE STOMACH WITH DISSEMINATION-A CASE REPORT-

Abstract

A 68-year-old man was admitted to our hospital with complaints of tremor and bilateral arm numbness. An MRI of the head showed multiple cerebral infarctions. Abdominal CT scanning detected a cystic tumor of the upper abdomen and angiography revealed that the tumor was fed by the splenic artery. Intraoperative findings determined that the tumor originated from the stomach with signs of dissemination. Total gastrectomy, distal pancreatectomy, splenectomy, and transverse colon resection were performed. The resected specimen was 30×23×10cm with signs of central necrosis. Histological and immunohistochemical studies of the specimen disclosed many mitosis, and that it was negative for vimentin, s-100, SMA, some areas were partially positive for NSE, and positive for CD34. This tumor was identified as a maligmant gastrointestinal stromal tumor, uncommitted type.