Abstract
BackgroundMalignant fibrous histiocytoma (MFH) is a common sarcoma affecting soft tissues of the body, especially of the extremities or trunk. Prognosis of the abdominal MFH is usually poor.Case presentationA 52-year-old female presented to our surgical outpatient clinic with a lower abdominal tumor that had been gradually increasing in size. Clinical examination revealed a firm, irregularly surfaced, fixed, painless, child-head-sized tumor located in her lower abdomen. Computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen revealed a polycystic tumor at the lower abdomen which was 15 × 13 × 11 cm in diameter and encased the colorectum to the left back side. A barium enema and a colonoscopy showed direct invasion to the rectum. In 2001, the tumor had been excised along with a low anterior resection of the rectum because of direct invasion. The origin of this tumor was the mesorectum. The weight of the excised tumor was 1,500 g, including 800 ml of a brown fluid. A histopathological diagnosis revealed a common type of MFH, in which mitotic figures are frequently seen.ConclusionThis patient has survived without recurrence, for approximately 8 years since the completed tumor resection. It is important to obtain a complete resection during the MFH treatment.
Highlights
Malignant fibrous histiocytoma (MFH) is a common sarcoma affecting soft tissues of the body, especially of the extremities or trunk
This patient has survived without recurrence, for approximately 8 years since the completed tumor resection
It is important to obtain a complete resection during the MFH treatment
Summary
Malignant fibrous histiocytoma (MFH) is a common sarcoma affecting soft tissues of the body, especially of the extremities or trunk [1,2,3]. We report a surgical case of MFH that originated from the mesorectum and affected the rectum. Case Report A 52-year-old female presented to our surgical outpatient clinic with a lower abdominal tumor that had been gradually increasing in size. She first noticed a fist sized, painless tumor about four months ago. Immunohistochemical analyses indicated that many of the tumor cells were positive for vimentin (Figure 4B), while tumor cells were negative for cytokeratins, desmin, S-100 protein, actins, c-kit, and CD34. These features are compatible with MFH of a common type. A postoperative follow-up CT revealed no recurrence of the MFH in any organs since the resection was completed
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