Abstract
Malignant fibrous histiocytoma (MFH), that occurs mainly in the extremities, is usually treated successfully by wide local excision. In contrast, when it occurs on the abdominal wall, as is less frequent, the prognosis may be poor, because radical surgical resection may be difficult, and in addition, there is little information on chemotherapy or radiation therapy fully effective against MFH. We experienced a recurrent case of MFH arising in the muscle layers of the abdominal wall. We treated it initially by a local excision, and postoperatively with a combination chemotherapy regimen, consisting of adriamycin, cyclophosphamide and vindesine sulfate. It recurred later, after a disease-free interval of 8 months. Thallium scanning and gallium scanning were performed preoperatively, and both scannings showed positive accumulation in the tumor site. From the histogram showing the changes in thallium accumulation at the foci of abnormal activity, it was difficult to discriminate a malignant lesion from a benign one. Nevertheless we belive thallium scanning is a useful tool for following up patients with MFH.
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