Abstract
Malignant fibrous histiocytoma (MFH) is an aggressive soft tissue sarcoma occurring in the late adulthood. It may rarely arise as a primary neoplasm in bone, but usually in the long bones and accounts for less than 1% of the malignant tumors of bone. Its presentation in the facial bones and skull is extremely rare. Malignant fibrous histiocytoma of bone is a highly malignant tumor that recurs, metastasizes, and commonly results in death despite aggressive surgical therapy. This article documents the clinical, radiographic and pathologic features of malignant fibrous histiocytoma of maxilla in a 45-year-old female patient and discusses the considerations related to the diagnosis.
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