Abstract
Malignant atrophic papulosis or Degos' disease is a rare multisystem vasculopathy of unknown cause that affects the skin, gastrointestinal tract, and central nervous system. The characteristic skin lesions are multiple asymptomatic papules with an atrophic white scarlike center surrounded by a telangiectatic border. Within weeks to years most patients develop infarctions mainly in the gastrointestinal and nervous systems. Systemic involvement portends a fatal prognosis. There have, however, been reports of cases with only cutaneous manifestations and a favorable prognosis.
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