Malignancy rates in thyroid nodules classified as benign according to the nodule size threshold of 4 cm

Abstract

SUMMARY Aim: The false negative rate of fine needle aspiration biopsy (FNAB) in large thyroid nodules ranges from 7.7% to 53%. The treatment of nodules that are 4 cm or larger is controversial because of the potential for false-negative FNAB results. In order to make treatment recommendations for nodules ≥4 cm in size, we compared the results of preoperative FNAB with thyroid surgery specimens. Materials and Methods: We evaluated patients who underwent thyroid surgery and had preoperative FNAB between 2017 and 2022. Patients were divided into two groups based on nodule size (