Abstract
Male subfertility contributing to about half of all involuntary childlessness is affected by a variety of genetic, behavioural and environmental factors. The value of the conventional semen quality analysis used to diagnose male infertility/subfertility is limited. The parameters recommended by the World Health Organization (WHO), sperm concentration, motility and morphology, are not sufficient to fully describe all the sperm biological properties needed to achieve fertilization and pregnancy, in spontaneous or assisted conception. During the last ten years, the assessment of sperm DNA integrity has emerged as a strong candidate as a new biomarker of semen quality that may help in the discrimination between infertile and fertile men and in predicting pregnancy outcome and risk of adverse reproductive events.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
