Abstract

Clinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date. To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients. We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD. We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitisthan female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients. Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.

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