Male breast cancer: Clinicopathological characteristics

Abstract

Male breast cancer is a very rare neoplasm which accounts for 1% of all breast cancers. In males breast tissue is much smaller than females and these cancer can easily invade the skin and pectoral muscles. : A 62-year old male patient with chief complaint of swelling in right breast since 6 months, the size of which had increased rapidly in last three months and associated with pain. Sonomammography reveals lobulated hypoechoic lesion in right retroareolar region. Fine nedle aspiration cytology reported as positive for carcinoma cells right breast. Right breast modifided radical mastectomy was performed. On histopathological findings reported as invasive breast carcinoma. RB score: 1+2+2=5 Grade I. The immunohistochemistry for hormone receptor showed positive estrogen receptor (ER) and progesterone receptor (PR), while HER2 was negative. All surgical margins and lymph nodes received from right axillary clearance were free from tumor. : We are presenting this extremely rare case of male breast cancer for its clinico-pathological findings. The tumor was medium size, with no axillary lymph node metastasis and on histopathology reported as invasive breast carcinoma grade I, which favored good prognostic criteria.