Abstract
Male and female rats differ in homeostatic shifts during pre-slaughter fear stress
Highlights
Stress is a multi-factorial phenomenon that affects functioning of different organs and systems of the body, including the immune system that is among the most vulnerable to stress
There was no difference in the level of this stress hormone in blood serum of male rats waiting in the cages for their slaughter for 20 and 40 min, while there was a >2.5 times increase in cortisol level in blood serum of the female rats waiting for their slaughter for the same periods of time
One may suggest that female rats are more sensitive to the pre-slaughter fear stress comparing with the male rats
Summary
Stress is a multi-factorial phenomenon that affects functioning of different organs and systems of the body, including the immune system that is among the most vulnerable to stress. The GCs are essential endocrine regulators of homeostasis of body functions and adaptation to the environmental changes, e.g. stress They regulate the essential body functions in mammals, as well as control cell metabolism, growth, differentiation, and apoptosis. They act as potent suppressors of the inflammation, and multiple immune-modulating mechanisms such as leukocyte apoptosis, differentiation, and cytokine production have been described [11]. Of special interest are changes in the organism of animals before a slaughter-induced stress, and sex-dependent differences in such mechanisms are not studied. This interest is caused by the bioethical reasons and the problems of production of high quality meat of the agricultural animals. The reason to perform such experiments was to look for sex-dependent differences in a response of rats to the slaughter fear-induced stress
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