Abstract
Aging influence over female fertility has been shown by many epidemiological studies, but less is know about male. However, sperm DNA fragmentation increases with age, and male age constitute an important risk factor for conceiving failure by assisted reproduction. Intracytoplasmic sperm injection (ICSI) allows men with reduced sperm production to reproduce. Patients with obstructive azoospermia can also be benefited as percutaneous epididymal sperm aspiration (PESA). Men who underwent vasectomy are a suitable model for studying age effect, as spermatogenesis is usually preserved.
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