Abstract

Chronic spontaneous urticaria (CSU) is a challenging condition to treat and it significantly affects quality of life. Bacterial, viral, parasitic, and fungal infections have been associated with triggering and/or perpetuating urticaria in certain individuals. There is a paucity of literature on CSU associated with Malassezia infection. We present a case series of five patients with CSU without angioedema in whom we observed temporal association of Malassezia infection with CSU. The presence of Malassezia was confirmed by clinical examination, Wood's lamp, and KOH examination. The patients with CSU experienced improvement after specific antifungal therapy. Malassezia infection may be associated with recurrent and chronic urticaria in a certain group of susceptible patients and thus specific targeted therapy against it might result in complete remission of urticaria along with clearing of the infection.

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