Abstract

Control, elimination, and eradication of malaria are one of the world’s greatest public health challenges, especially in Sub-Saharan Africa.The expectation of producing an effectivevaccine has been on for 40 years, but the recent breakthrough announcement of a malaria vaccine showing some level of protection among infants and children 3-4 years post vaccination seems like an excellent starting point. The globally accepted strategy for the control of malaria rely on chemotherapy, but unfortunately the overreliance on chemotherapy without proper control of drug usage and diagnosis has encouraged the selection of drug-resistant parasites, significantly contributing to the problem. Therefore, the prospects of malaria eradication rest heavily on integrated approaches that would include chemotherapy, vector control, and manipulation of environmental and ecological characteristics, and vaccination.

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