Abstract

Presented in a question-and-answer form this article discusses: the availability of necessary tools for tackling parasite resistance to drugs and mosquito resistance to insecticides; the effectiveness of the Roll Back Malaria horizontal program; the accuracy of malaria control strategies; and the probability of the Roll Back Malaria program’s controlling malaria in 2010 and 2025. It is projected that in 2010 over 80% of the population in every village in malarious areas of Africa will be sleeping under insecticide-impregnated mosquito nets every night. Fever clinics with effective antimalarial drugs will exist within 5 km of 80% of the villages. However the strategies of patient management selective treatment and chemoprophylaxis during pregnancy bednet distribution and epidemic containment will have little long-term impact on transmission. In 2025 over 90% of persons in rural malarious areas will be sleeping under long-duration insecticide-impregnated bed nets and using insecticide-impregnated clothing and soap with effective nontoxic insect repellents. Malarial first-line therapy chloroquine and pyrimethamine-sulfadoxine will be replaced by new low-cost antimalarial drugs. New treatment and prevention interventions will be existent through the use of improved genetic understanding of mosquitoes parasites and human susceptibility to malaria.

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