Maladies systémiques à expression cutanée et infection à VIH sur peaux foncées: Aspects épidémio-cliniques et thérapeutiques à Abidjan (Côte d’Ivoire)

Abstract

Objective: The objective of the study was to describe the epidemiological, clinical, therapeutic and evolutionary aspects of systemic diseases (SD) with cutaneous expression associated with HIV infection and to identify the circumstances of their occurrence. Patients and methods: This were a cross-sectional, descriptive, and analytical study of the records of patients hospitalized or followed up at the Voluntary Counselling and Testing Unit (VCT) of the Dermatology Department of the University Hospital of Treichville, from January 2005 to December 2014. Results: We recorded 63 patients with MS during this period, 13 of whom were HIV positive (20.6%). MS of HIV positive patient was more frequent after 24 years (mean age: 49.5 years) and a male predominance (58.3%). HIV 1 was involved in all cases with a mean CD4 count of 190/mm3 [18-521] at diagnosis of MS. HIV-associated MS were psoriasis (7 cases), cutaneous lymphoma (2 cases), Goujerot-Sjögren syndrome (1 case), pyoderma gangrenosum (1 case), systemic scleroderma (1 case) and sarcoidosis (1 case). They were circumstances of discovery of HIV infection in 7 cases, expression of therapeutic failure in 3 cases and expression of an immune restoration syndrome in 3 cases. The 13 patients received concomitant antiretroviral treatment and the specific treatment of the systemic pathology associated with an anti-inflammatory in some cases. Conclusion: The association of MS and HIV infection is rare. Their etiologies are dominated by psoriasis in Abidjan. A well-conducted interrogation to determine the chronology of events, assisted by biological examinations, allows the circumstance of occurrence to be identified.