Maladaptive Eating Behaviors and Metabolic Profile in Patients Submitted to Bariatric Surgery: a Longitudinal Study.

Abstract

This study aims to investigate relations between maladaptive eating behaviors (MEB) and metabolic profile in patients submitted to bariatric surgery. Longitudinal study including 70 patients before (T0), in the first year after surgery assessment (T1), and the second year after surgery assessment (T2). A face-to-face clinical interview assessed MEB at T0 and T2. Blood samples were collected at T0, T1, and T2 to assess fasting plasma glucose (FPG), glycated hemoglobin (HbA1c), insulin, insulin resistance (IR), and triglycerides (TG). Mixed model analyses with growth curves tested the differences between patients with MEB (M group) and non-MEB patients (NM group) on the course of metabolic parameters, while controlling for total weight loss and type of surgery. No differences between both groups were reached for levels of FPG (F(1, 140)=2.936, p=0.089), HbA1c (F(1, 96)=0.099, p=0.754), insulin (F(1, 121)=0.146, p=0.703), IR (F(1, 60)=0.976, p=0.327), and TG (F(1, 128)=0.725, p=0.396). All parameters improved from T0 to T1 for both groups. A distinct trend on the course of metabolic markers in the M group but not the NM group is observed, presenting an increase in HbA1c levels, insulin, and TG levels. Both groups progressed favorably in the first 12months of surgery. MEB may be associated with a trend for deterioration of metabolic profile after 12months of surgery. The study should be replicated with longer-term assessments and a larger sample size.