Abstract
The scientific review reveals the relevance of the problem of persistent disability in patients with mental disorders as one of the most important indicators of public health. It has been shown that organic pathology plays an important role in increasing of incidence of disability due to mental disorders in people of working age. In addition, the clinical and epidemiological data of recent years, confirming the large scatter of disability rates across regions and the poorly understood clinical factors that determine disability in organic mental disorders, are presented. The need for further study of predictors of health deterioration as well as risk factors for persistent disability in order to solve the problems of preventing disability and to develop personalized programs of medical and social rehabilitation is discussed.
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