Abstract
Maintenance of Genome Stability
Highlights
This review offers a better understanding of the biological roles of this unique Posttranslational modifications (PTMs) in maintaining genome stability
Kaminsky et al [10] reviewed recent progress on the role of the DDR in the etiology of various brain degenerative diseases (BDDs), and summarized the evidence suggesting that BDDs involve the dysfunction of glial cells
Li and Liu [11] provided a comprehensive review on the effect of topoisomerase 1 (TOP1) on genome stability
Summary
Cells have evolved several response systems to tackle numerous DNA lesions in order to maintain their genome integrity. To understand how cells regulate to maintain their genomic stability is of fundamental importance. Six mini-reviews are included in this special issue, which cover various aspects of mechanisms underlying the maintenance of genome stability and related diseases.
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