Abstract
Dudek et al 1 Dudek A.Z. Wang X. Gu L. et al. Randomized study of maintenance pemetrexed versus observation for treatment of malignant pleural mesothelioma: CALGB 30901. Clin Lung Cancer. 2020; (https://doi.org/10.1016/j.cllc.2020.06.025, accessed August 5, 2020) Abstract Full Text Full Text PDF PubMed Scopus (18) Google Scholar have presented the results of the “Randomized Study of Maintenance Pemetrexed Versus Observation for Treatment of Malignant Pleural Mesothelioma: CALGB [Cancer and Leukemia Group B] 30901” in the current issue of Clinical Lung Cancer. The goal of the study was to determine whether continuation maintenance therapy with pemetrexed would improve the progression-free survival (PFS) of patients with malignant pleural mesothelioma whose tumors had not progressed during frontline treatment with pemetrexed and a platinum agent. The study was closed because of slow accrual, likely owing to the widespread acceptance of maintenance pemetrexed for mesothelioma in the United States and competing clinical trials. Of the 49 patients who had been randomized to pemetrexed or observation and analyzed, no improvement was seen in PFS or overall survival (OS).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
