Abstract
A mail-in data collection system makes it possible for beamline users to collect diffraction data without visiting a synchrotron facility. In the mail-in data collection system at SPring-8, users pack crystals into sample trays and send the trays to SPring-8 via a courier service as the first step. Next, the user specifies measurement conditions and checks the diffraction images via the Internet. The user can also collect diffraction data using an automated sample changer robot and beamline control software. For distant users there is a newly developed data management system, D-Cha. D-Cha provides a graphical user interface that enables the user to specify the experimental conditions for samples and to check and download the diffraction images using a web browser. This system is now in routine operation and is contributing to high-throughput beamline operation.
Highlights
At SPring-8, the RIKEN structural genomics beamlines I and II (BL26B1 and BL26B2) have been constructed to contribute to structural genomics research
To achieve high-throughput protein crystallography, we have developed two special components: an automated sample changer robot, SPACE (SPring-8 precise automatic cryo-sample exchanger) (Ueno, Hirose et al, 2004), which can change up to 100 crystals in a diffractometer, and the beamline control software BSS (Ueno et al, 2005), which can perform successive data collection by controlling beamline devices, including SPACE, and managing the data collection schedule
To better accommodate the new system to the needs of distant users and a laboratory information management system (LIMS) for beamline operation and experiments, we have developed a new operation system that enables users to use the beamlines from their own laboratories
Summary
At SPring-8, the RIKEN structural genomics beamlines I and II (BL26B1 and BL26B2) have been constructed to contribute to structural genomics research. The first method is used by the Swiss Light Source at the Paul Scherrer Institut (SLS/PSI) and the Advanced Photon Source (Advanced Photon Source, 2006). These users send their samples to a beamline, and datasets collected by beamline staff are returned to the users. At the Stanford Synchrotron Radiation Laboratory remote data can be collected by using the beamline control application Blu-Ice and the. We have developed a mail-in data collection system which is a combination of the mail-in and remote access methods. We discuss in detail the mail-in data collection at SPring-8 using the web database application D-Cha (database for crystallography with home-lab arrangement), which enables remote operation and mail-in data collection
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