Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020

Abstract

Acute kidney injury (AKI) is the sudden loss of organ function and the third leading cause of mortality after bleeding and brain trauma among admitted patients. There is a paucity of epidemiological data concerning AKI in Sub-Saharan African countries including Ethiopia with predominant admission of chronic cases. Methods: An institution-based cross-sectional study was conducted from 15 August- 14 October 2020. Epi-Data version 3.2 was used for data entry. In addition, STATA/14 was used for analysis. A Logistic regression model was used to determine the association of independent variables with the outcome variable and adjusted odds ratios (AOR) with 95% confidence interval was used to estimate the strength of the association at P<0.05. Result: Two hundred eighty-eight (288) card of inpatient were selected for analysis making the overall response rate 97.8%. The mean (±SD) age of the respondents was 44.16 (±18.29) years. The overall magnitude of AKI was 23.32% (95%CI: 18.91--29.36). Cases at baseline having hemoglobin level≤10.9mg/dl (AOR=11.4: 95%CI: 4.2, 31.2), bing cancer cases 6.87 (AOR=6.87; 95%CI: 1.76--26.73, P<0.005), and having creatinin levels > 1.36 mg/dl (>121 Micromole/L) was 5.78 (AOR=5.77; 95%CI: 1.93--17.27), were significantly associated with AKI. Conclusions: According to KDIGO-definitions of AKI, the high magnitude was reported among hospitalized patients and predicted by being cases of cancer, anemic and creatinine levels were significantly associated with AKI.