Abstract
Abstract. An elevated arterial pressure with left ventricular hypertrophy (LVH) is one of the major causes of global mortality. The present study was aimed to analyze the value of MCG in the detection of LVH in patients with and without coronary artery disease (CAD). The study included 212 subjects: 109 CAD patients (81 male, 61.6 ± 10 years), 24 with LVH and 103 patients (56 male, 59.3 ± 10.2 years) without coronary stenoses ≥ 50%, 14 with LVH. MCG recordings were obtained at 9 pre-thoracic sites using an unshielded four-channel SQUID-magnetometer. Current density vector maps were generated during the ST–T-interval and analyzed using a classification system with a scale from 0 (normal) to 4 (grossly abnormal). The results showed no statistically significant differences in the relative frequency of map classes except for class 1, which occurred more often in patients without LVH. Especially in patients without CAD and no LVH the maps of class 1 occurred with the highest frequency. The presence of LVH seems to change current density distribution comparable to CAD. These changes are too discrete to allow a clear detection of LVH in CAD or no CAD patients. Improved discrimination may be possible by taking MCG signal strength into account.
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