Abstract
Two wireless, passive remote query magnetism-based glucose sensors, which operate in combination with a mass and volume changing glucose responsive polymer, are presented. One sensor design is based upon the magnetostatic coupling of magnetically soft thin-film elements; as the polymer volume changes in response to glucose concentration so does the magnetostatic coupling between elements. In response to a time varying magnetic field, upon reversal of the magnetization vector of the elements the magnetostatic coupling determines the time rate of change of magnetic flux, and hence the amplitude of the voltage spike generated in a pick-up coil. The other sensor consists of a free-standing magnetoelastic thick-film, coated with a thin layer of the glucose responsive polymer. In response to a time varying magnetic field the sensor mechanically vibrates at a characteristic resonant frequency; the characteristic resonant frequency of the sensor linearly tracks the change in mass of the glucose responsive polymer.
Highlights
Sensors for blood glucose concentration are of great medical and commercial interest
Most glucose sensors are based upon the amperometric response of electrodes coated with glucose responsive materials; as the glucose concentration changes so does the electrical properties of the responsive materials, and the electrical current measured across the electrodes [1,2,3,4]
In this paper we present two wireless, passive magnetism-based glucose sensors that operate in combination with a mass and volume changing glucose responsive polymer
Summary
Sensors for blood glucose concentration are of great medical and commercial interest. The distance between the magnetic elements changes as the polymer swells and shrinks in response to changes in glucose concentration, changing the magnetostatic coupling between elements. The other sensor is based on the mass-sensitive change in the magnetoelastic resonant frequency of an amorphous ferromagnetic glass ribbon coated with the glucose responsive polymer.
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