Abstract
Chronic alcohol abuse is a significant problem for a large number of individuals, especially in the population of U.S. Veterans. Research to date has documented some of the long-term deleterious effects associated with chronic abuse. Cognitive difficulties may include impairments in short-term memory, paired associate learning, visual-spatial skills, complex problem-solving, and psychomotor functioning. Neuroradiographic findings show that cortical atrophy and white matter changes are prominent at late stages of alcoholism, but intermediate effects are less well documented. From a brain functional perspective, evoked potential studies demonstrate that subjects in the late stages of alcohol abuse show changes in P3 amplitude for both the visual and auditory stimuli.
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