Abstract

Magnetic resonance spectroscopy (MRS) can be applied for analyzing and evaluating the treatment response to human brain tumors. It is a valuable and noninvasive technique for identifying metabolites including choline-containing compounds, N-acetyl aspartate, lactate, and creatine/phosphocreatine. This technique provides important clinical information allowing more specific diagnosis, including differentiating the brain tumors from abscesses, identifying the tumoral characteristic of the studied lesion, better characterizing brain tumors, and establishing an extended local assessment of morphological abnormalities detected in conventional magnetic resonance imaging (MRI). In this chapter, MRS (single- and multi-voxel) techniques in diagnosis, follow-up and analysis of brain tumors, and grading of primary brain tumors are highlighted.

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