Abstract
IntroductionMantle cell lymphoma is a rare non-Hodgkin's lymphoma. It is a subtype of B-cell lymphoma with frequent involvement of the bone marrow and the gastrointestinal tract. Isolated parotid gland involvement seldom occurs. Here we report an unusual case of isolated infiltration of the parotid gland by mantle cell lymphoma. The aim of our study is to correlate magnetic resonance imaging findings with the histological features of the disease. To the best of our knowledge, no similar radiological findings of mantle cell lymphoma have been published before.Case presentationA 72-year-old Caucasian woman presented with a painful left parotid enlargement. She was diagnosed with mantle cell lymphoma involving the left submandibular gland seven years prior to presentation. Her whole body CT scan showed the absence of pathologically enlarged lymph nodes. However, a magnetic resonance imaging showed enlargement of her left parotid gland and an abnormal parenchyma with mixed-type solid and cystic lesions. A biopsy of her left parotid gland and subsequent histological examination confirmed a mantle cell lymphoma (common variant) relapse.ConclusionAlthough rare, the involvement of parotid gland with mantle cell lymphoma must be considered in the differential diagnosis of parotid tumors.
Highlights
Mantle cell lymphoma is a rare non-Hodgkin’s lymphoma
Conclusion: rare, the involvement of parotid gland with mantle cell lymphoma must be considered in the differential diagnosis of parotid tumors
Mantle cell lymphoma (MCL) is a rare lymphoma that accounts for approximately 5% to 7% of non-Hodgkin’s lymphomas (NHL). It is usually characterized by an aggressive clinical course with a median overall survival of two to five years [1]
Summary
Mantle cell lymphoma is a rare non-Hodgkin’s lymphoma. It is a subtype of B-cell lymphoma with frequent involvement of the bone marrow and the gastrointestinal tract. We report an unusual case of isolated infiltration of the parotid gland by mantle cell lymphoma. The aim of our study is to correlate magnetic resonance imaging findings with the histological features of the disease. Mantle cell lymphoma (MCL) is a rare lymphoma that accounts for approximately 5% to 7% of non-Hodgkin’s lymphomas (NHL). It is usually characterized by an aggressive clinical course with a median overall survival of two to five years [1]. According to Argatoff et al, the isolated extranodal location of the disease has been referred in 25% of cases, whereas salivary glands are rarely affected (only 3% of reported cases) [1]. We have correlated its appearance at MRI with its histological findings
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