Abstract
Background:Solitary fibrous tumors (SFTs) are rare and can be misdiagnosed because of their various radiological appearances.Purpose:To clarify the characteristic MRI findings of SFTs by analyzing their radiological-pathological correlation.Material and Methods:Nine consecutive patients with SFT who underwent magnetic resonance imaging (MRI) prior to surgery were analyzed. Eight patients underwent contrast-enhanced MRI, and three underwent dynamic MRI. Radiological-pathological correlation analysis, co-occurrence matrix, run-length matrix, and histogram analysis were performed to assess the relationship between pathological findings T1- and T2-weighted images (T1-WI and T2-WI).Results:All nine lesions ranged in size from 20 to 36 mm. Seven lesions were located in the superior portion of the retrobulbar space found outside of the muscle cone, and two lesions in the inferior portion were located within it. No significant correlation was observed between the amount of collagenous tissue and the qualitative evaluation of the signal on T1-WI and T2-WI. Kurtosis on T2-WI was significantly correlated with the amount of collagenous tissue (ρ = –0.97, p < 0.0001) and endothelial cells (ρ = –0.49, p = 0.0479).Conclusion:Kurtosis in the histogram analysis on T2WI showed a strong correlation with the amount of collagenous tissue.
Highlights
No significant correlation was observed between the amount of collagenous tissue and the qualitative evaluation of the signal on T1-WI and T2-WI
Kurtosis on T2-WI was significantly correlated with the amount of collagenous tissue (ρ = –0.97, p < 0.0001) and endothelial cells (ρ = –0.49, p = 0.0479)
Kurtosis in the histogram analysis on T2WI showed a strong correlation with the amount of collagenous tissue
Summary
Solitary fibrous tumors (SFTs) are rare spindle-cell neoplasms originating from the mesenchymal tissue. Zhang et al reported that the marked enhancement displayed in hyperintense lesions and the isointense areas displayed on T2-WI with washout are characteristics that may help differentiate SFTs from other tumors in the orbit [6]. There are few reports describing the association between imaging data and the pathology of SFTs. Recently, texture analysis has been used to detect features of images that are difficult to determine by visual observation. The purpose of this study was to clarify the characteristic MRI findings of orbital SFTs by conducting a radiologicalpathological correlation analysis. Solitary fibrous tumors (SFTs) are rare and can be misdiagnosed because of their various radiological appearances. Purpose: To clarify the characteristic MRI findings of SFTs by analyzing their radiologicalpathological correlation
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