Abstract
AbstractMultiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are two common inflammatory, demyelinating and neurodegenerative diseases of the CNS. It is clinically crucial to differentiate these two diseases since they have distinct treatment strategy and prognosis. MRI has an increasingly important role in the differential diagnosis of NMOSD from MS. Conventional MRI is sensitive and its objective is to demonstrate the lesion characteristics, including lesion number, size, and distribution, while the advanced MRI can offer the structural, functional, and other microscopic information. We herein review the current advances in the understanding of MRI study of the brain, spinal cord, and optic nerve in MS and NMOSD.
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