Abstract
To determine the outcome of treating distal interphalangeal joint collateral ligament (DIJCL) desmopathy using magnetic resonance imaging (MRI)-guided ligament injection. Medical records of 13 adult horses diagnosed with DIJCL desmopathy using low-field MRI and treated by MRI-guided ligament injection of mesenchymal stem cells and/or platelet-rich plasma (PRP) were reviewed. Information collected included signalment, MRI diagnosis, treatment type, time to resolution of lameness, and level of exercise after treatment. Collateral ligament inflammation was diagnosed as a cause of lameness in 13 horses. MRI was used to guide the injection of the injured DIJCL. All lameness attributed to DIJCL desmopathy resolved with the resulting level of performance at expected (10) or less than expected (3). Injection of the DIJCL can be safely completed in horses standing in a low-field magnet guided by MRI as previously demonstrated in cadaver specimens. The positive response in all horses suggests that administration of stem cells or PRP along with rest and appropriate shoeing may be a safe and useful treatment for DIJCL desmopathy.
Highlights
Treatment of tendon and ligament injuries by injection with either mesenchymal stem cells (MSC) or platelet-rich plasma (PRP) is reported to improve healing and eventual outcome [1, 2]
All horses included in the study had moderate-to-severe uniaxial distal interphalangeal joint collateral ligament (DIJCL) desmopathy
Either MCS combined with PRP or PRP alone was selected for injection based on the clinician’s preference and cost to the client
Summary
Treatment of tendon and ligament injuries by injection with either mesenchymal stem cells (MSC) or platelet-rich plasma (PRP) is reported to improve healing and eventual outcome [1, 2]. These techniques have been used in tendons and ligaments of the metacarpus and metatarsus, where ultrasound can be used to direct the injection [1]. Collateral Ligament Desmitis Treatment enlargement, changes in border definition, and increased signal intensity within the ligament [10] These changes correspond to degenerative changes observed histologically, including collagen degeneration, fissure formation, and fibrocartilaginous metaplasia, and are often accompanied with osseous change in the ligament insertion [10, 11]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
