Magnetic resonance imaging features of primary central nervous system lymphoma in immunocompetent patients

Abstract

Objective To study the magnetic resonance imaging (MRI) features of primary central nervous system lymphoma in immunocompetent patients and assess the value of MRI in the diagnosis of the tumor. Methods Plain and enhanced MRI data of 15 immunocompetent patients with primary CNS lymphoma were analyzed retrospectively. Results A total of 18 lesions were detected in the 15 patients, including 14 (77.8%) supratentorial and 4 (22.2%) infratentorial ones. Seven lesions (38.9%) had obvious necrosis or hemorrhage, and leptomeninges metastasis was found in 2 patients. Fifteen lesions displayed isointensity on T2WI and TI WI. All the lesions showed markedly homogeneous enhancement. Seventeen of the lesions presented with mild or moderate mass effect. Conclusion Primary CNS lymphomas in immunocompetent patients are commonly seen in the supratentorial region. The MRI features of the lesions include isointensity on T2WI and TIWI, homogeneous enhancement, and mild or moderate mass effect. Key words: Primary central nervous system lymphoma; Immunocompeten patients; Magnetic resonance