Abstract
To estimate the diagnostic possibilities of magnetic resonance imaging (MRI) techniques and three-dimensional multivoxel proton magnetic resonance spectroscopy (MRS) in patients with clinical suspicion of prostate carcinoma. 36 patients suspected to have prostate carcinoma underwent MRI with dynamic contrast enhanced study and MRS at 1.5T MRI unit using a pelvic phased array coil. MRI and MRS results were correlated with pathohystological findings after radical prostatectomy and standard biopsy with 12 or 24 cores or guided biopsy. Out of 44 detected prostate carcinomas, 38 (86.36%) demonstrated low T2W signal intensity while pathognomonic contrast enhancement has been detected in 40 (91%) carcinomas. MRS showed (Cho+Cr)/Ci ratio mean value of 3.52 in carcinoma, and 0.14 in normal prostatic tissue (p < 0.01). MR techniques, both nonenhanced and contrast enhanced when combined with MRS can provide reliable diagnostic results in the evaluation of prostate carcinoma even by use of pelvic phased array coil at 1.5T unit.
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