Magnetic polymer enhanced hybrid capsules prepared from a novel Pickering emulsion polymerization and their application in controlled drug release

Abstract

Magnetic polymer enhanced hybrid capsules (MPEHCs) were successfully prepared from a novel Pickering emulsion polymerization. The resultant products were characterized by Transmission electron microscopy (TEM), Scanning electron microscopy (SEM), Fourier transform infrared spectrum (FTIR), Thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS) and Vibration sample magnetometer (VSM). It was proved that the MPEHCs consist of SiO 2 outer shell and magnetic polymer inner shell with particle sizes from 0.8 μm to 2 μm and thickness about 140 nm. The MPEHCs were applied as a drug carrier to study their controlled release behaviors and ibuprofen was used as a model drug. The curve of release behaviors of ibuprofen exhibited a typical sustained release pattern, indicating that the MPEHCs could be applied as a promising drug vehicle for controlled release systems.