Abstract

Magnetic-plasmonic heterodimer nanostructures synergistically present excellent magnetic and plasmonic characteristics in a unique platform as a multipurpose medium for recently invented biomedical applications, such as magnetic hyperthermia, photothermal therapy, drug delivery, bioimaging, and biosensing. In this review, we briefly outline the less-known aspects of heterodimers, including electronic composition, interfacial morphology, critical properties, and present concrete examples of recent progress in synthesis and applications. With a focus on emerging features and performance of heterodimers in biomedical applications, this review provides a comprehensive perspective of novel achievements and suggests a fruitful framework for future research.

Highlights

  • Aqueous colloids of heterodimer nanoparticles are a fascinating class of multimodal hybrid structures, which have appeared in the last decade and increasingly attracted many attentions

  • Hyperthermia cancer treatment, magnetic resonance imaging (MRI), and magnetically targeted drug delivery have been chosen for the magnetic part, and photothermal therapy and bioimaging were chosen for the plasmonic part

  • Plasmonic characteristics are associated to the response of nanoparticles to electromagnetic radiation in the specific wavelength ranges of ultra-violet (UV), visible, and near infra-red (NIR) light, which are used for different biomedical applications, including photothermal therapy and imaging approaches [69,70,71]

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Summary

Introduction

Aqueous colloids of heterodimer nanoparticles are a fascinating class of multimodal hybrid structures, which have appeared in the last decade and increasingly attracted many attentions. The positive roles of different magnetic-plasmonic heterodimers for various biomedical diagnostic and therapeutic treatments have been reported, including magnetic resonance imaging (MRI) [46,47,48], cellular uptake [49,50,51], plasmon imaging [52,53], X-ray computed tomography (CT) [54], positron emission tomography (PET) [55], photothermal therapy (PTT) [56–.

HotInProperties for Biomedical
Hot Properties for Biomedical Applications
Magnetic Characteristics
Plasmonic Features
Structure Design
Electronic Nature of Components
Metallic—Metallic
Metallic—Nonmetallic
Nonmetallic—Nonmetallic
Interfacial Morphology
Dumbbell-Like
Dumbbell-Like Shape
Mosaic
Rod-Shape
Janus Beads
Further Specific Shapes
Summary
Tailored
Tailored Properties of Selected Heterodimers
Magnetic Features
Plasmonic Properties
M-H curves of superparamagnetic CoFe
T at the
Electronic Structure
Biocompatibility and Physiochemical Stability
Improved Performances
Magnetic Hyperthermia
Photothermal Therapy
Omagnitude
10. Therapeutic
Bioimaging
Findings
Conclusions and Future Perspective
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