Abstract
Magnetic biosensors are promising candidates for low-cost point-of-care biodiagnostic devices. For optimal efficiency it is crucial to minimize the time and complexity of the assay protocol includi ...
Highlights
In recent years, much research has focused on nanomaterials and their ability to elevate the performance of various biosensor techniques used in diagnostic applications.[1]
Possibilities for protocol simplifications for a DNA biodetection principle relying on hybridization of magnetic nanobeads to rolling circle amplification (RCA) products are investigated
Possibilities for protocol simplifications for a biodetection principle relying on hybridization of probe-functionalized magnetic nanobeads to rolling circle amplification products have been evaluated
Summary
Much research has focused on nanomaterials and their ability to elevate the performance of various biosensor techniques used in diagnostic applications.[1] One prominent nanomaterial emerging from these studies is magnetic nanoparticles.[2,3,4] Apart from requirements concerning sensitivity, selectivity and reliability, biosensors should ideally be easy to handle and provide a fast response.[5,6] integration and automation of all reaction steps in sample preparation with sample analysis is essential for successful development of a fully automated diagnostic test. A homogeneous assay including as few steps and/or changes in variables as possible is desirable and integration of complex multistep protocols has been challenging to date.[7] magnetic micro- and nanoparticles have been proven useful for automation of sample preparation in bioanalytical devices by serving as solid phase supports to enable reagent exchange and washing in multi-step assays.[8,9]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
