Magnetic mesoporous molecularly imprinted polymers based on surface precipitation polymerization for selective enrichment of triclosan and triclocarban

Abstract

Novel magnetic mesoporous molecularly imprinted polymers (MMIPs) were prepared based on surface precipitation polymerization using Triclosan (TCS) as template and methacrylic acid as functional monomer. The synthesized MMIPs-TCS were applied to the adsorbent of magnetic solid-phase extraction (MSPE) coupled with HPLC for the enrichment and determination of TCS. The MMIPs-TCS were characterized by fourier-transform infrared spectrometry (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption transmission, and vibrating sample magnetometry. Under the optimum condition, the MMIPs-TCS-MSPE-HPLC method shows low limits of detection (LODs) (0.20–0.90 μg L−1) and limits of quantification detection (LOQs) (0.66–2.97 μg L−1), wide linear ranges from 10.0 to 1000 μg L−1 for each compound with exception of 2,4,6-TCP from 20.0 to 1000 μg L−1, and acceptable reproducibility (relative standard deviation, RSD <6.6% for intra-day, RSD <8.1% for inter-day). The satisfactory recoveries were in the range of 89.5%–108.4% with good RSDs less than 8.0% at the three spiked levels of 20, 50 and 80 μg L−1. Moreover, the adsorption experiments show the MMIPs-TCS possess rapid binding affinity, excellent magnetic response, specific selectivity and high adsorption capacity toward TCS with a maximum adsorption capacity of 1955.8 μg g−1.