Abstract
A series of cobalt (Co) and its oxides based nanoparticles were synthesized by using hyperbranched polyester polyol Boltorn H20 as a platform and sodium borohydride as a reducing agent. UV, FT-IR, XRD, NTA, and TEM methods were employed to obtain physicochemical characteristics of the products. The average diameter of Co nanoparticles was approximately8.2±3.4 nm. Their magnetic properties, including hysteresis loop, field-cooled, and zero field-cooled curves were investigated. The nanoparticles exhibit superparamagnetism at room temperature, accompanied by magnetic hysteresis below the blocking temperature.
Highlights
Magnetic nanoparticles exhibit specific physical properties and are of great interest because of their prospective applications in biology and medicine [1,2,3,4,5] for magnetic cell separation [6], magnetically controlled delivery of anticancer drugs [7, 8], magnetic resonance imaging (MRI) contrast enhancement [9, 10], and hypothermia treatment [11]
We describe the synthesis of Co nanoparticles via the matrix of nontoxic hyperbranched polyester polyol based on 2,2-bis-hydroxymethyl-propionic acid
Synthesis of organic-inorganic nanocomposites was carried out in the following way: the first stage is the formation of complex forms of Co2+, hyperbranched polyester polyols (HBPO); the second stage was the synthesis of polymer-metal nanocomposites by the chemical reduction method [37]
Summary
Magnetic nanoparticles exhibit specific physical properties and are of great interest because of their prospective applications in biology and medicine [1,2,3,4,5] for magnetic cell separation [6], magnetically controlled delivery of anticancer drugs [7, 8], magnetic resonance imaging (MRI) contrast enhancement [9, 10], and hypothermia treatment [11]. An additional advantage of HBP matrix in the synthesis of practically useful metal nanoparticles is their biosimilar topological structure and simplicity of synthesis [33, 34] Earlier it was shown by some authors how series of magnetic cobalt (Co) nanoparticles could be stabilized by a poly-amidoamine (PAMAM) dendrimer [28], polyamine dendrimers with a trimesyl core [29], and Journal of Nanotechnology hydroxyl-terminated PAMAM dendrimers [30]. For the purposes of cell sorting, medical diagnosis, and controlled drug delivery, the strategy for the synthesis of magnetic cobalt nanoparticles is based on the use of nontoxic, biosimilar, and biodegradable hyperbranched polymers and dendrimers. Such compounds include hyperbranched polyester polyols (HBPO) of various generations [36]. We describe the synthesis of Co nanoparticles via the matrix of nontoxic hyperbranched polyester polyol based on 2,2-bis-hydroxymethyl-propionic acid
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