Magnetic ceramics based on hydroxyapatite modified by particles of M-type hexagonal ferrite for medical applications

Abstract

Magnetic bioceramics based on hydroxyapatite Ca5(PO4)3OH and particles of the M-type hexagonal (barium or calcium) ferrite with a high bioactivity and magnetic characteristics providing hyperthermal treatment of oncology diseases has been developed and studied. The phase composition, microstructure, and magnetic properties of the synthesized bioceramics have been determined. It has been shown that the synthesized biomaterial consists of the biocompatible matrix with the apatite structure into which particles of hexagonal ferrite are incorporated. The magnetic parameters of the synthesized ceramics are substantially higher than those of the bioglass ceramics modified by iron oxides that have been used in medicine, which suggests good potential and effectiveness of application of the created ceramics for medical purposes. Thus, a new class of magnetic bioceramics combining hydroxyapatite Ca5(PO4)3OH, which exhibits good properties in biocompatibility and bioactivity, with particles of the M-type hexagonal ferrite, which possess high magnetic characteristics, has been created.