Abstract
Magnesium sulfate overdose resulting in maternal cardiac arrest: a case report
Highlights
A case is presented which highlights the importance of reconsideration of potential differential diagnoses when clinical improvement after therapeutic interventions is lacking
Magnesium sulfate has been shown in several large, well designed randomized trials as well as systematic reviews to reduce the incidence of further eclamptic seizures more effectively than phenytoin, diazepam and other anticonvulsants [4,5]
In order to highlight these pitfalls we present a case of severe magnesium sulfate overdosing resulting in maternal cardiac arrest and need for peri-mortem cesarean delivery
Summary
Seizures occur in less than 1 % of all pregnancies and can be caused by many different conditions [1]. In order to highlight these pitfalls we present a case of severe magnesium sulfate overdosing resulting in maternal cardiac arrest and need for peri-mortem cesarean delivery. Two more episodes of tonic-clonic seizures occurred and the patient was given six more ampoules of Cormagnesin® 400 mg. Thereafter she became hypotensive and bradycardic and eventually went into asystole cardiac arrest. On the MRI scan taken eight days after delivery, a right frontal lesion identifiable, which was read by the radiologist as cavernoma with hemorrhage or intracerebral hemorrhage due to a fall as part of a seizure event (Figure 1b). One month after discharge, a noncystic, periventricular leukomalacia I° was diagnosed by MRI and a neurodevelopmental follow-up showed hyperextension tendency with otherwise unremarkable findings
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