Magnesium Sulfate Nebulizer versus Ketamine Nebulizer in Decreasing Incidence and Severity of Post Operative Sore Throat with Endotracheal Intubation in Adults

Abstract

Background: Endotracheal intubation is the prominent cause of airway mucosal injury which results in postoperative sore throat (POST), with an incidence of 21%–65%. Although this complication is minor, if left unresolved, it produces significant agony and annoyance to the patient. Aim of the Work: to compare efficacy of magnesium/ nebulizer versus ketamine nebulizer in decreasing postoperative sore throat incidence, severity and duration with fixed endotracheal tube intra cuff pressure at or below 20 cm H2O using handheld tracheal cuff pressure monitor in adults ASA (American Society of Anesthesiologists) I-II in 20-60 years age group of either sex in operations less than 2 hours. Methodology: our study included 90 adult patients, status I-II (ASA I-II) in the age group 20-60 years, of either sex undergoing operation under general anesthesia (GA) scheduled for a day case surgery and operation time less than 2 hours with fixation of endotracheal tube cuff at 20 cm H2O using hand held tracheal cuff pressure monitor (Pressure Gauge) and checked every half hour till end of surgery and maintained at or below 20 cm H2O. Results: Our study showed reduction in POST incidence and severity after preoperative magnesium sulfate nebulization in all time points 0, 2, 4, 8, 12 and 24 hours postoperative, so it was proved that magnesium nebulizer has great role in reduction of incidence, severity and duration of POST. Conclusion: we concluded that preoperative magnesium sulfate nebulization reduce incidence and severity of POST and it is more effective than preoperative ketamine nebulization.