Abstract
Purpose. To evaluate the variations in macular thickness in young Chinese myopic persons and the association with axial length (AL), spherical equivalence refraction (SE), age, intraocular pressure, and sex. Methods. In total, 133 young Chinese myopic subjects between 18 and 30 years of age were selected. The macular thickness was assessed using third-generation optical coherence tomography. AL, intraocular pressure, and SE were also measured. Results. The mean central foveal thickness was 191.1 ± 15.3 µm. The macula was consistently thinner in women than in men. Central foveal thickness had a significant positive correlation with AL and a negative correlation with SE. In the inner and outer regions, the macular thickness had a positive correlation with SE and negative correlation with AL. Conclusions. The retina was thinner in women than in men. Associated with myopic progression and AL extension, the central foveal thickness increased, while the retinal thickness of the inner and outer regions decreased.
Highlights
Myopia is a public health problem in China and other countries in East Asia [1]
The purpose of our study was to evaluate the variations in macular thickness in young Chinese myopic patients with different diopter (D) degrees and to assess the influences of axial length, refractive error, age, and sex using time domain-Optical coherence tomography (OCT) (TD-OCT)
There were no significant differences in mean age, axial length, and spherical equivalence refraction (SE) refraction between men and women
Summary
In high myopia patients (generally greater than −6.00 diopters (D)), scleral ectasias are relatively frequent and involve the posterior pole of the eye, leading to poor visual prognosis in adult life [2]. The risks of retinal detachment, chorioretinal atrophy, pigmentary degeneration, and posterior staphyloma increase with severity of myopia and increase in axial length [3]. Optical coherence tomography (OCT) is a noninvasive, cross-sectional imaging technique that can measure macular thickness and is highly reproducible [4]. This technology allows in vivo measurement of retinal thickness to enhance the understanding of the pathophysiology of myopia and its relationship with the development of other ocular diseases
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