Macular thickness and volume of myopic eyes measured using spectral‐domain optical coherence tomography

Abstract

Purpose: The aim was to evaluate macular thickness and volume of young myopic eyes measured using Cirrus HD spectral‐domain optical coherence tomography (Cirrus HD‐OCT; Carl Zeiss Meditec, Dublin, CA, USA).Methods: Three hundred and thirty‐six eyes of 336 healthy young subjects (aged 19 to 25) with various degrees of refractive error and axial length were recruited. Average macular thickness, foveal thickness, inner/outer macular thickness and macular volume were measured using Cirrus HD‐OCT. The association between refractive error/axial length and retinal thickness/volume was analysed.Results: The mean average macular thickness, foveal thickness, inner/outer macular thickness and macular volume were 280.7 ± 10.9 µm, 258.1 ± 18.4 µm, 320.6 ± 12.7/277.3 ± 12.3 µm and 10.1 ± 0.4-mm3, respectively. Average macular thickness, inner/outer macular thickness and macular volume decreased and foveal thickness increased as the degree of myopia/axial length increased (p‐values less than 0.01). The correlation between axial length and macular measurements remained significant when refractive error was controlled (p ≤ 0.017); however, when axial length was controlled, the association between refractive error and macular thickness/volume was no more significant (p ≥ 0.084).Conclusions: In healthy young myopic eyes, thinner macular thickness, lower macular volume and thicker foveal thickness were associated with longer axial length.