Macular involvement in non infectious intermediate, posterior and panuveitis

Abstract

AbstractPurpose To study macular involvement in non infectious intermediate, posterior and panuveitis.Methods The data of 201 eyes in 118 patients with diagnosed non infectious intermediate, posterior or panuveitis examined between January 2007 and June 2012 were retrospectively reviewed. All patients underwent complete ophthalmic examination with fluorescein angiography and optical coherence tomography (OCT) to assess macular involvement.Results Uveitis was due to behcet’s disease in 62 eyes(30.8%), sarcoidosis in 22 eyes (10.9%), VKH in 24 eyes (11.9%), sympathetic ophthalmia in 1 eye (0.5%), birdshot chorioretinopathy in 2 eyes (1%), and multiple sclerosis in 2 eyes (1%). At initial examination, 54 eyes (27.2%) demonstrated macular involvement which consisted in macular edema (ME) in 32 eyes (15.9%), serous retinal detachment in 29 eyes(14.4%), epiretinal membrane (ERM) in 8 eyes (3.9%), macular atrophy in 2 eyes (1%), vitreo‐retinal traction in 1 eye (0.5%), macular hole in 1 eye (0.5%) , and active macular chorioretinitis in 1 eye (0.5%). During follow up, 16 eyes (8%) developed macular complications including ME in 6 eyes(3%), ERM in 5 eyes (2.5%), and macular atrophy in 5 eyes (2.5%).Conclusion Macular involvement,especially macular edema, is common in non infectious intermediate, posterior and panuveitis. It may lead to irreversible visual impairment. Thus, recognition of macular morphological characteristics by performing both OCT and fluorescein angiography in uveitic disease may facilitate earlier diagnosis and the initiation of specific treatment.