Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements

Abstract

We read with interest the article by Nouri-Mahdavi and associates evaluating the ganglion cell/inner plexiform layer (GC/IPL) measurements in early glaucoma. 1 Nouri-Mahdavi K. Nowroozizadeh S. Nassiri N. et al. Macular ganglion cell/inner plexiform layer measurements by spectral domain-optical coherence tomography for detection of early glaucoma and comparison to retinal nerve fiber layer measurements. Am J Ophthalmol. 2013; 156: 1297-1307 Abstract Full Text Full Text PDF PubMed Scopus (115) Google Scholar They found no significant improvement in performance of GC/IPL parameters with both regional and global GC/IPL performing equally well for glaucoma detection. This is very encouraging and informative where other algorithms may be used for improving glaucoma detection. Such information regarding clinical application of imaging in glaucoma diagnosis is indeed useful for any clinician. 2 Mori S. Hangai M. Sakamoto A. Yoshimura N. Spectral-domain optical coherence tomography measurement of macular volume for diagnosing glaucoma. J Glaucoma. 2010; 19: 528-534 Crossref PubMed Scopus (89) Google Scholar , 3 Medeiros F. Zangwill L. Bowd C. Vessani R. Susannajr R. Weinreb R. Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography. Am J Ophthalmol. 2005; 139: 44-55 Abstract Full Text Full Text PDF PubMed Scopus (505) Google Scholar Yet there are a few concerns that we would like to communicate. Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer MeasurementsAmerican Journal of OphthalmologyVol. 156Issue 6PreviewTo evaluate the performance of ganglion cell layer/inner plexiform layer (GCL/IPL) measurements with spectral-domain optical coherence tomography (Cirrus HD-OCT) for detection of early glaucoma and to compare results to retinal nerve fiber layer (RNFL) measurements. Full-Text PDF ReplyAmerican Journal of OphthalmologyVol. 158Issue 1PreviewWe greatly appreciate Drs Padhy and Rao's comments regarding our study.1 We would like to address the criticisms they raised as follows. Full-Text PDF