Abstract
The aim of this research was to determine the incidence, risk factors and perinatal outcome of the macrosomic infants (birth weight > or = 4000 g). The retrospective research was performed using a case-control study conducted at Mostar Clinical Hospital. Total of 379 women gave singleton term births to macrosomic newborn in the period from January 1st, 2004 to December 31st, 2005 (observed group). Another 379 singleton normal birthweight term newborns (birth weight < 4000 g, but not small for gestational age), of the same maternal parity and age, who were delivered in the same period, formed the control group. The incidence of macrosomic births was 13, 1%. In the study group, significantly higher number of cases of postdatism (> 42 weeks of gestation) (P<0,001), maternal obesity (prepregnancy BMI> 26 kg/m2) (P<0,001), gestational diabetes mellitus (P=0,033), hypertension (P=0,025) and male infant (P<0,001) were observed. Cesarean delivery (P<0,001), intrapartal complications (cephalopelvic disproportion P<0.001, perineal trauma P=0,042) and newborn birth trauma (clavicular fracture P=0,038, brachial palsy P=0,021) occurred significantly more often in the macrosomic group. There was only one fetal death in the macrosomic group. In the control group there were no cases of perinatal deaths. To conclude, it is important to emphasize the significance of proper diagnosis of fetal macrosomia and management of macrosomic birth, since we have seen a growing number of macrosomic births during the last decades, and have faced a problem of increased risks of adverse perinatal outcome.
Highlights
In regard to possible labor complications, fetal macrosomia is usually defined as birth weight ≥ g, regardless of the gestational age
Macrosomic infants can be determined in the case of birth weight over percentile for their gestational age
Macrosomia has been associated with an increased rate of operative deliveries because macrosomic infants have an increased incidence of birth trauma which included clavicular and humeral fracture, brachial palsy, perinatal asphyxia and death due to shoulder dystocia and prolonged birth (, - )
Summary
In regard to possible labor complications, fetal macrosomia is usually defined as birth weight ≥ g, regardless of the gestational age. Maternal risk factors for macrosomia have included multiparity, advanced age, nonsmoking, previous macrosomic infants, obesity, excessive pregnancy weight gain, diabetes mellitus, hypertension, prolonged pregnancy ( , ). The antenatal diagnosis of fetal macrosomia is an important clinical and medico legal issue because it has been related to an increase in labor complications and birth injuries. Considering increased risks of complications related to delivery of macrosomic fetuses, the aim of this research was to determine the incidence, risk factors and perinatal outcome of the macrosomic infants and to compare the results of the available studies
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