Macroscopical and microscopical study of placenta in normal and in pregnancy induced hypertension

Abstract

Placenta was an indicator of maternal and foetal disorders. Many of the disorders of pregnancy which are associated with high prenatal morbidity and mortality are accompanied by changes in placental histology. The current works was an analysis of gross and histological changes of placenta in hypertensive disorders of pregnancy. A total of 50 placentas are studied 25 placenta from hypertensive pregnant mothers and 25 from non hypertensive pregnant mothers. The morphmetric parameters in hypertensive group revealed that there is an increase in the mean placental weights, mean placental diameter and mean birth weights in comparison with normal group.
 The analysis of macroscopic placental changes showed decrease in the mean number of cotyledons and increase in mean number of calcified areas as well as an increase in the number of marginal insertion of umbilical cord.The histological appearance of placenta in hypertensive pregnant mothers revealed increase in hyalinized spots and areas of calcification also a medial coat proliferation of medium sized blood vessels are observed . In conclusion the hypertensive disorder of pregnancy well reflected on mother placenta.