Macroscopic Examination of Placental Vascularization with a Corrosive Agent in Pregnant Women Diagnosed with Thrombophilia

Abstract

The normal development of the placenta is a major factor in the fetus s growth and development, whilst the maternal-fetal placental vasculature is essential in this regard. During placentation, there is an ongoing process, which combines angiogenesis with vasculogenesis, as demonstrated by numerous studies, which reveal important roles of various known angiogenic factors, while other studies show the roles of different classes of factors in vascular morphogenesis nonspecific to the placenta. The method used in the case of our study is a standardized method of the Laboratory of Anatomy and Embryology, Victor Babes University of Medicine and Pharmacy, Timişoara, for over 50 years. The making of corrosion concoction followed the recipe of the laboratory using type AGO II plastic substances, differently colored and then subjected to the corrosive action of hydrochloric acid. During the routine check outs all the pregnant woman�s were diagnosed with thrombophilia. The examination of the placental parameters - shape, weight, thickness - is important as a preliminary stage for the study of the placental architecture. The normal placental development remains a major factor in the growth and development of the fetus, and the maternal-fetal placental vasculature is essential in this regard. Placental angiogenesis has a different local component of angiogenesis, found in other anatomical regions.