Abstract
Macrophage phagocytosis of intact senescent neutrophils (PMNs) is an important mechanism of PMN clearance from the resolving inflamed site which is determined by programmed cell death or apoptosis in the aging PMN. 1 J Clin Invest. 1989; 83: 865-875 Crossref PubMed Scopus (1349) Google Scholar This leads to recognition of the aged PMN as “senescent self” and phagocytosis by macrophages via a mechanism in which the Arg-Gly-Asp adhesion signal and a macrophage β3 integrin, the vitronectin receptor (VnR), play critical roles. 2 Nature. 1990; 343: 170-173 Crossref PubMed Scopus (700) Google Scholar
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
