Abstract

Macrophage activation syndrome (MAS) is a serious, potentially fatal complication of rheumatic diseases, which is seen most frequently in systemic onset juvenile idiopathic arthritis (soJIA).

Highlights

  • Macrophage activation syndrome (MAS) is a serious, potentially fatal complication of rheumatic diseases, which is seen most frequently in systemic onset juvenile idiopathic arthritis. This case is reported to expose the difficulties of diagnosis and management of MAS due to soJIA in a patient with liver transplantation

  • When she was transferred to our clinic, physical examination was notable for temperature ranged from 40° C to above and maculopapular rash

  • Intravenous methylprednisolone (IV) methylprednisolone was administered at a dose of 30 mg/kg/day for three days and switched to prednisolon 2 mg/kg/day

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Summary

Introduction

Macrophage activation syndrome (MAS) is a serious, potentially fatal complication of rheumatic diseases, which is seen most frequently in systemic onset juvenile idiopathic arthritis (soJIA). Macrophage activation syndrome due to systemic onset juvenile idiopathic arthritis in a case with liver transplantation Introduction Macrophage activation syndrome (MAS) is a serious, potentially fatal complication of rheumatic diseases, which is seen most frequently in systemic onset juvenile idiopathic arthritis (soJIA). Objectives This case is reported to expose the difficulties of diagnosis and management of MAS due to soJIA in a patient with liver transplantation.

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