Abstract

The paper provides a short review about synthesis and research of macromolecules with carbohydrate residues. In recent years, research in the field of carbohydrate chemistry was focused on design and production of artificial glycoconjugates analogues containing the same structural and functional elements, i.e. neoglycoconjugates. Synthetic carbohydrate structures may possess similar natural properties, simulate various biological processes or stages used in biochemical research in obtaining antibodies to carbohydrate determinants, serve as selective delivery vectors into cells and be used as affinity chromatography sorbents. The paper also discusses the principles of glyconanoparticle (GNP) formation and their possible exploration in glycobiology and material science. Common ways of neoglycoconjugates research to study or to assess interactions with various classes of compounds, as well as for the creation of artificial antibacterial vaccines, biomimetics and contrast agents in magnetic resonance imaging (MRI) were reflected.

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