Abstract
Synthetic routes to the macrocyclic polyamine derivatives (1) and (3) are described, together with an investigation of the complexing properties of the triamines (1d) and (3d) with primary alkylammonium cations. Macrotricyclic and macrotetracyclic compounds may be obtained from the macrocycle (1) by a stepwise procedure whereas macrocycle (3b) can be converted into a macrotricyclic derivative in a one step alkylation procedure. The alkylation of the tetrahydropyrimidone (18) with αα′-dibromo-m-xylene gives the calix[4] arene analogue (19) which adopts the ‘cone’(21a) and ‘1,3-alternate’(21b) conformations. The macrocyclic hexa-amine (23) may be synthesized by a simple alkylation procedure whereas the octa-amine (27) required a systematic stepwise synthesis. The hexa-amine salt (23)·6 HBr shows selectivity in forming inclusion complexes with the dicarboxylate anions –O2C(CH2)nCO2–.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Perkin Transactions 1
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
